Do Disorders of Movement Cause Movement Disorders and Dementia?
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چکیده
منابع مشابه
Do Disorders of Movement Cause Movement Disorders and Dementia?
Neurons require long-distance microtubule-based transport systems to ferry vital cellular cargoes and signals between cell bodies and axonal or dendritic terminals. Considerable progress has been made on developing a molecular understanding of these processes and how they are integrated into normal neuronal functions. Recent work also suggests that these transport systems may fail early in the ...
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Neurodegenerative disease, including dementia, extrapyramidal degeneration, and motor system degeneration, is a growing public health concern and is quickly becoming one of the top health care priorities of developed nations. The primary function of anatomic neuroimaging studies in evaluating patients with dementia or movement disorders is to rule out structural causes that may be reversible. L...
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Alzheimer’s disease (AD) and Parkinson’s disease (PD) represent the most common neurodegenerative disorders, and while AD is the most prevalent cause of dementia, PD, the commonest bradykinetic movement disorder, has a cumulative prevalence of dementia of 75-90% (PD dementia – PDD) particularly in patients with a disease duration of 10 years or longer. At the opposite end of the spectrum of mov...
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TAKE HOME MESSAGES 1. Movement disorders involve the basal ganglia and associated structures, often affecting the globus pallidus (the output target of the striatum) 2. Abnormal involuntary movements are classified as hypokinetic or hyperkinetic, and are subclassified byspeed, duration and whether or not they are rhythmic. 3. Parkinsonism is characterized by the presence of at least 2 of the 4 ...
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Movement disorders are neurological conditions affecting speed, fluency, quality, and ease of movement. Deep brain stimulation (DBS) is used to treat advanced Parkinson's disease, essential tremor, and dystonia. Possible target sites for DBS include the ventral intermediate nucleus of the thalamus, the globus pallidus internus, and the subthalamic nucleus. High-frequency DBS leads to a kind of ...
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ژورنال
عنوان ژورنال: Neuron
سال: 2003
ISSN: 0896-6273
DOI: 10.1016/s0896-6273(03)00630-5